Doctor's Best Best French Grape Extract (60 mg) 90 caps
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Best French Grape Extract is a whole grape extract produced from premium wine grapes. Processed without chemical solvents and using a low-temperature extraction method, Best French Grape Extract contains proanthocyanidins, polyphenols, flavonoids and resveratrol. Made from the whole grape, including seed, skin, and stem Best French Grape Extract is a full-spectrum product extracted from the seeds, skins, and stems of select hybrid grapes. The unique extraction process is done in France using locally grown grapes. The final product is purely extracted with water and grain alcohol only. This ensures a product free of chemical residues, and absorption is optimized because the extract is water soluble. Best French Grape Extract retains the natural deep purple grape color. Quality Guaranteed Best French Grape Extract is continually analyzed by an independent laboratory using the Porter Method, an industry-accepted test of grape-extract quality. The Porter Value of Best French Grape Extract ranges from 290 to 320. These are exceptionally high measurements indicative of a product rich in beneficial active ingredients.

Ingredients

Benefits Rich in Natural Antioxidants, including resveratrol Best French Grape Extract delivers a wide profile of natural constituents present in wine grapes, including polyphenols, proanthocyanidins (OPCs), gallic acid, ellagic acid, quercetin, catechin, epicatechin and other valuable components. Many of these substances are powerful antioxidants, which are under investigation for their potential health benefits. Best French Grape Extract also contains resveratrol, a potent antioxidant present in the grape skin. In a study recently conducted at the University of Chicago, resveratrol demonstrated significant in vitro free-radical inhibiting ability and antimutagenic activity, as well as anti-inflammatory activity in test animals.2 Protects health of capillaries OPCs derived from grapes have been investigated for their protective effect on capillaries, the small blood vessels subject to free-radical-induced injury. OPCs show the ability to prevent the formation of lipid peroxides, a type of free-radical that can attack lipid molecules in epithelial tissue, which forms the lining of capillary walls.3 OPCs also protect capillary tissues from breakdown by enzymes such as collagenase, elastase and hyaluronidase.3 Protects Heart Health There is growing interest in the ability of wine grape polyphenols to protect LDL cholesterol from oxidation. In a 1993 study published in The Lancet, Frankel, et al found that phenolic substances present in wine acted as electron donors to inhibit copper-catalyzed oxidation of LDL.4 It is now believed that oxidized LDL is a major factor in the buildup of plaque deposits in blood vessels. In its unoxidized or “native” state, LDL cholesterol accumulates in blood-vessel walls only to a limited degree. On the other hand, oxidized LDL is readily absorbed by macrophages present in arterial walls, forming “foam cells.” This is the initial stage in plaque formation. Much of the value of dietary antioxidants may center around mitigating LDL oxidation. It has been suggested that the benefits of polyphenols may help explain the so-called “French Paradox,” the relatively low mortality rate from heart disease found in regions with high consumption of red wine. In summary, the broad range of natural grape antioxidants in Best French Grape Extract may protect overall cardiovascular health in several ways: 1) Reduction of oxidative stress (free radicals), 2) Protection of LDL cholesterol against oxidation, 3) Preventing formation of lipid peroxides which can attack capillary cell membranes, and 4) Inhibition of enzymes that break down capillary tissues.

Safety Suggested Adult Use: As a dietary supplement, take one capsule three times daily, or as directed by a nutritionally informed health care provider.

Scientific References 1. Gluck, G. Cyvex Technologies, Irvine, CA, Technical Bulletin, 03 February 1997. 2. Facino, R. M., et. al. “Free radicals scavenging action and antienzyme activities of procyanidines from Vitis vinifera” Arzneim.-Forsch. (1994) 44(I), Nr. 5:592-601. 3. Frankel, E.N., et. al. “Inhibition of oxidation of human low density lipoprotein by phenolic substances in red wine” Lancet (1993) 341:454-57. 4. Jang, M., et. al. “Cancer chemoprotective activity of resveratrol, a natural product derived from grapes” Science Vol. 275, 10 January1997.