High Absorption CoQ10 contains pure, vegetarian
source Coenzyme Q10 in a base of rice powder, plus Bioperine®, an herbal
extract that enhances CoQ10 absorption.
Benefits
Boosts Cellular Energy Production*
Coenzyme Q10 is a vitamin-like nutrient found in the human body. Essential
to life, CoQ10 works at the cellular level to produce metabolic energy in
the form of ATP.*1,2 CoQ10 serves as a vital link in
the “electron transport chain,” which is the final step in the production of
ATP inside cells. Lacking adequate CoQ10, cells become energy-deficient.
When cells are nourished with optimal levels of CoQ10, tissues, organs and
systems function optimally.
Strengthens and Protects the Heart*
The heart is the hardest-working muscle in the body. Because of its high
energy requirements, the heart needs to be well supplied with CoQ10 at all
times. The body’s highest concentration of CoQ10 occurs in heart muscle
tissue. (Heart muscle cells contain large numbers of mitochondria.) Numerous
clinical studies have demonstrated significant improvements in heart
function with oral administration of CoQ10.3,4,5
Supports Immune Function*
When the immune system goes into battle for us, immune cells need large
amounts of energy to carry out their defensive functions. CoQ10 is required
for this energy to be available. Experimental research on animals has shown
that CoQ10 enhances immune functions such as the activity of phagocytes, and
antibody production.* Age-related immune suppression has been observed in
mice given CoQ10.6
Antioxidant Protection
CoQ10 is a versatile antioxidant.* The reduced form of CoQ10, ubiquinol-10,
has been found to protect LDL against peroxidation by free radicals more
effectively than vitamin E.* CoQ10 stabilizes membranes,* thus protecting
them from free-radical damage.7,8,9
Benefits the Gums*
A number of studies have shown that CoQ10 supports repair of gingival (gum)
tissue. Gingival tissues in people with periodontal disease have been found
deficient in CoQ10. In several double-blind clinical trials, oral
administration of CoQ10 has resulted in significant improvements.10,11
Many Clinical Benefits
Research studies and clinical reports suggest CoQ10 has a broad range of
applications stemming from its ability to support the heart and
cardiovascular system, the immune system, cellular energy production, liver
function, nerves, and muscles.*
CoQ10 — Vitamin E’s Partner
In vitro studies suggest CoQ10 in combination with vitamin E protects LDL
cholesterol from oxidation more effectively than vitamin E alone. Protecting
LDL from being oxidized by free radicals is now thought to be important for
cardiovascular health.9,12
Bioperine® — A Bioavailability-Enhancing Phytonutrient
Bioperine® is a natural extract derived from black pepper that enhances
nutrient absorption.* Preliminary trials on humans have shown significant
increases in the absorption of nutrients consumed along with Bioperine®. In
a recent study (publication pending), the administration of 5 mg of
Bioperine® together with 120 mg of CoQ10 per day resulted in a 32% increase
in CoQ10 absorption after 21 days.13 (This is
especially important for individuals who have impaired absorption of
fat-soluble nutrients such as CoQ10.)
Safety
Suggested Use: As a dietary supplement, take 1 capsule daily. For maximum
absorption, take with a fat-containing meal.
The black pepper fruit extract used in this product is Bioperine, a patented
standardized extract containing 95% piperine.
Scientific References
1. Folkers, K., Wolaniuk, A., Progress in biomedical and clinical research
on coenzyme Q10. Drugs Exptl. Clin. Res. 1984; X(7):513-517.
2. Lenaz, G., et. al., “The essentially of coenzyme Q for bioenergetics and
clinical medicine.” Drugs Exptl. Clin. Res. 1985; XI(8):547-556.
3. Morisco, C., Trimarco, B., Condorelli, M., “Effect of coenzyme Q10
therapy in patients with congestive heart failure: a long-term multicenter
randomized study.” Clin. Investig. 1993; 71:S134-S136.
4. Mortensen, S.A., Vadhanavikit, S., Muratsu, K., Folkers, K., “Coenzyme
Q10: clinical benefits with biochemical correlates suggesting a scientific
breakthrough in the management of chronic heart failure.” Int. J. Tiss Reac.
1990; XII(3):155-62.
5. Poggesi, L., et. al., Effect of coenzyme Q10 on left ventricular function
in patients with dilative cardiomyopathy. Current Therapeutic Research 1991;
49(5):878-886.
6. Folkers, K., Wolaniuk, A., “Research on coenzyme Q10 in clinical medicine
and in immunomodulation.” Drugs Exptl. Clin. Res. 1985; XI(8):539-545.
7. Littarru, G.P., et. al., “In vitro effect of different ubiquinones on the
scavenging of biologically generated O2.” Drugs Exptl. Clin. Res. 1985;
XI(8):529-532.
8. Littarru, G.P. Lippa, S., “Coenzyme Q and antioxidant activity: facts and
perspectives.” Drugs Exptl. Clin. Res. 1984; X(7):491-96.
9. Stocker, R., Bowry, V.W., Frei, B., “Ubiquinol-10 protects human low
density lipoprotein more efficiently against lipid peroxidation than does
alpha-tocopherol.” Proc. Natl. Acad. Sci. 1991; 88:1646-1650.
10. Hansen, I., Iwamoto, Y., Kishi, T., Folkers, K., “Bioenergetics in
clinical medicine. IX. Gingival and leucocyte deficiencies of coenzyme Q10
in patients with periodontal disease.” Research Communications in Chemical
Pathology and Pharmacology 1976; 14:729-738.
11. Wilkinson, E. Arnold, R., Folkers, K., “Treatment of Periodontal and
Other Soft Tissue Diseases of the Oral Cavity with Coenzyme Q” (in)
Biomedical and Clinical Aspects of Coenzyme Q 1977; 1:251-266. K. Folkers
and Y. Yamaura, eds., Elsevier Science Publishing Co., N.Y.
12. Thomas, S., Neuzil, J., Stocker, R., “Cosupplementation with coenzyme Q
prevents the prooxidant effect of alpha-tocopherol and increases the
resistance of LDL to transition metal dependant oxidation initiation.”
Arteriosclerosis, Thrombosis and Vascular Biology 1996; 16(5):687-96.
13. Badmaev, V., Majeed, M., “Comparison of Coenzyme Q10 (CoQ10)
bioavailability when ingested alone and in combination with Bioperine®.”
Sabinsa Corporation Research Report. 1996 (unpublished).
*Above statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
