Benefits
• Boosts Cellular Energy
Production*
Coenzyme Q10 is a
vitamin-like nutrient found in the human body. Essential to life, Co Q10
works at the cellular level to produce energy for metabolism in the form of
ATP.*1,2 Co
Q10 serves as a vital link in the "electron transport chain," which is the
final step in the production of ATP in the mitochondria of cells.
Without an adequate supply
of Co Q10, cells can become energy-deficient, slowing down a number of
critical cellular processes. When cells are nourished with optimal levels of
Co Q10, tissues, organs and systems function properly.
• Strengthens and Protects
the Heart*
The heart is the hardest
working muscle in the body. Because of its high energy requirements, the
heart needs Co Q10 at all times. The highest concentration of Co Q10 in the
human body occurs in heart muscle tissue. Numerous clinical studies have
demonstrated significant improvements in heart function with oral
administration of Co Q10.3,4,5 Studies are increasingly showing
an ability of Co Q10 to improve energy production in heart cell mitochondria
by bypassing defective components in the respiratory chain, as well as to
protect heart tissue from the effects of chronic oxidative stress.14
• Supports Immune Function*
When the immune system goes
into battle for us, immune cells need large amounts of energy to carry out
their defensive functions. Co Q10 is required for this energy to be
available. Experimental research on animals has shown that Co Q10 enhances
immune functions such as the activity of phagocytes, and antibody
production.6
• Antioxidant protection*
Co Q10 is a versatile
antioxidant.* The reduced form of Co Q10, ubiquinol-10, has been found to
protect LDL against peroxidation by free radicals more effectively than
vitamin E.* Co Q10 stabilizes membranes,* thus protecting them from free
radical damage.7,8,9 In addition, studies have shown that
CoQ10’s potent free radical scavenging properties extend to brain tissue,
where CoQ10 may protect neurons from the ravages of oxidative damage.13
Along with conferring protection to heart and brain tissues, CoQ10 has also
been shown to enhance the levels of other antioxidant vitamins in the
circulation, such as vitamins, A, C and E.13
• Benefits the Gums*
A number of studies have
shown that Co Q10 supports repair of gingival (gum) tissue. Gingival tissues
in people with periodontal disease have been found deficient in Co Q10. In
several double-blind clinical trials, oral administration of Co Q10 has
resulted in significant improvements.10,11
• Co Q10 – Vitamin E's
Partner
In vitro studies
suggest Co Q10 in combination with vitamin E protects LDL cholesterol from
oxidation more effectively than vitamin E alone. Protecting LDL from being
oxidized by free radicals is a major factor in maintaining cardiovascular
health.9,12
• Diverse clinical
benefits*
A number of research
studies and clinical reports suggest a broad range of potential benefits
from Co Q10 supplementation, stemming from its ability to support the heart
and cardiovascular system, the immune system, cellular energy production,
liver function, nerves, and muscles. *
*This statement has not been evaluated by the
Food and Drug Administration. This product is not intended to diagnose,
treat, cure or prevent any disease.
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Scientific References
1. Folkers, K., Wolaniuk,
A. Progress in biomedical and clinical research on coenzyme Q10. Drugs
Exptl. Clin. Res. 1984; X(7):513-517.
2. Lenaz, G., et. al. The
essentially of coenzyme Q for bioenergetics and clinical medicine. Drugs
Exptl. Clin. Res. 1985; XI(8):547-556.
3. Morisco, C., Trimarco,
B. Condorelli, M., Effect of coenzyme Q10 therapy in patients with
congestive heart failure: a long-term multicenter randomized study. Clin
Investig 1993; 71:S134-S136.
4. Mortensen, S.A.,
Vadhanavikit, S., Muratsu, K., Folkers, K. Coenzyme Q10: clinical benefits
with biochemical correlates suggesting a scientific breakthrough in the
management of chronic heart failure. Int. J. Tiss Reac. 1990;
XII(3):155-62.
5. Poggesi, L., et. al.
Effect of coenzyme Q10 on left ventricular function in patients with
dilative cardiomyopathy. Current Therapeutic Research 1991;
49(5):878-886.
6. Folkers, K., Wolaniuk,
A. Research on coenzyme Q10 in clinical medicine and in immunomodulation.
Drugs Exptl. Clin. Res. 1985; XI(8):539-545.
7. Littarru, G.P., et. al.
In vitro effect of different ubiquinones on the scavenging of biologically
generated O2. Drugs
Exptl. Clin. Res. 1985; XI(8):529-532.
8. Littarru, G.P. Lippa, S.
Coenzyme Q and antioxidant activity: facts and perspectives. Drugs Exptl.
Clin. Res. 1984; X(7):491-96.
9. Stocker, R., Bowry, V.W.,
Frei, B., Ubiquinol-10 protects human low density lipoprotein more
efficiently against lipid peroxidation than does alpha-tocopherol. Proc.
Natl. Acad. Sci. 1991; 88:1646-1650.
10. Hansen, I., Iwamoto,
Y., Kishi, T., Folkers, K. Bioenergetics in clinical medicine. IX. Gingival
and leucocyte deficiencies of coenzyme Q10 in patients with periodontal
disease. Research Communications in Chemical Pathology and Pharmacology
1976; 14:729-738.
11. Wilkinson, E. Arnold,
R., Folkers, K. Treatment of Periodontal and Other Soft Tissue Diseases of
the Oral Cavity with Coenzyme Q. (in) Biomedical and Clinical Aspects of
Coenzyme Q 1977; 1:251-266. K. Folkers and Y. Yamaura, eds., Elsevier
Science Publishing Co., N.Y.
12. Thomas, S., Neuzil, J.,
Stocker, R. Cosupplementation with coenzyme Q prevents the prooxidant effect
of alpha-tocopherol and increases the resistance of LDL to transition metal
dependant oxidation initiation. Arteriosclerosis, Thrombosis and Vascular
Biology 1996; 16(5):687-96.
13. Borek, C. Co-Q10
Energizes the Heart and Brain. Nutrition Science News 1999; 4(7):
322-324.
14. Rosenfeldt FL, et al. Coenzyme Q10 protects the aging heart against
stress: studies in rats, human tissues, and patients. Ann N Y Acad Sci.
2002 Apr; 959: 355-9 |
